Evaluation of Disease Resistance Potential of Diorganotin Complexes in Some Bacteria and Fungi

Savita Belwal; R. V. Singh

doi:doi:10.11648/j.sjc.20130105.13

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Evaluation of Disease Resistance Potential of Diorganotin Complexes in Some Bacteria and Fungi

Savita Belwal, R. V. Singh

Published in Science Journal of Chemistry (Volume 1, Issue 5)

Received: 5 December 2013 Published: 10 January 2014

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Abstract

The reaction of diphenyltin dichloride and dimethyltin dichloride with the ligands of Schiff base lead to the formation of a new series of bioactive organotin (IV) complexes. The isolated products are coloured solids soluble in most of the organic solvents. The bonding and coordination behaviour of these compounds are discussed by the support of electronic, infrared and multinuclear magnetic resonance (1H, 13C and 119Sn NMR) spectral studies. These investigations suggest that the ligands act in a bidentate manner, coordination through the sulphur and nitrogen atoms. Trigonal bipyramidal geometry is proved for 1:1 metal complexes and hexacoordinated geometry is assigned for 1:2 metal complexes. All the complexes are monomeric in nature as indicated by their molecular weight determinations. Conductivity measurements show them to be non-electrolyte as the conductance values in DMF lie in the range of 10-12 ohm-1 cm2 mol-1. Schiff bases and their corresponding organotin complexes have also been screened for their antifungal and antibacterial activities and found to be quite active in this respect. Testing of ligands and their organotin complexes for disease resistance have been successfully studied in vitro and in vivo experiments. Results were quite encouraging and these were compared with the standard pesticides Bavistin and Streptomycin.

Published in	Science Journal of Chemistry (Volume 1, Issue 5)
DOI	10.11648/j.sjc.20130105.13
Page(s)	67-73
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2014. Published by Science Publishing Group

Keywords

Organotin (IV) Complexes, Thio- and Semi-Ligands, Spectral Studies, Biochemical Studies, Toxicity, in Vitro and in Vivo Study

References

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APA Style

Savita Belwal, R. V. Singh. (2014). Evaluation of Disease Resistance Potential of Diorganotin Complexes in Some Bacteria and Fungi. Science Journal of Chemistry, 1(5), 67-73. https://doi.org/10.11648/j.sjc.20130105.13

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ACS Style

Savita Belwal; R. V. Singh. Evaluation of Disease Resistance Potential of Diorganotin Complexes in Some Bacteria and Fungi. Sci. J. Chem. 2014, 1(5), 67-73. doi: 10.11648/j.sjc.20130105.13

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AMA Style

Savita Belwal, R. V. Singh. Evaluation of Disease Resistance Potential of Diorganotin Complexes in Some Bacteria and Fungi. Sci J Chem. 2014;1(5):67-73. doi: 10.11648/j.sjc.20130105.13

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@article{10.11648/j.sjc.20130105.13,
  author = {Savita Belwal and R. V. Singh},
  title = {Evaluation of Disease Resistance Potential of Diorganotin Complexes in Some Bacteria and Fungi},
  journal = {Science Journal of Chemistry},
  volume = {1},
  number = {5},
  pages = {67-73},
  doi = {10.11648/j.sjc.20130105.13},
  url = {https://doi.org/10.11648/j.sjc.20130105.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjc.20130105.13},
  abstract = {The reaction of diphenyltin dichloride and dimethyltin dichloride with the ligands of Schiff base lead to the formation of a new series of bioactive organotin (IV) complexes. The isolated products are coloured solids soluble in most of the organic solvents. The bonding and coordination behaviour of these compounds are discussed by the support of electronic, infrared and multinuclear magnetic resonance (1H, 13C and 119Sn NMR) spectral studies. These investigations suggest that the ligands act in a bidentate manner, coordination through the sulphur and nitrogen atoms. Trigonal bipyramidal geometry is proved for 1:1 metal complexes and hexacoordinated geometry is assigned for 1:2 metal complexes. All the complexes are monomeric in nature as indicated by their molecular weight determinations. Conductivity measurements show them to be non-electrolyte as the conductance values in DMF lie in the range of 10-12 ohm-1 cm2 mol-1. Schiff bases and their corresponding organotin complexes have also been screened for their antifungal and antibacterial activities and found to be quite active in this respect. Testing of ligands and their organotin complexes for disease resistance have been successfully studied in vitro and in vivo experiments. Results were quite encouraging and these were compared with the standard pesticides Bavistin and Streptomycin.},
 year = {2014}
}

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TY - JOUR
T1 - Evaluation of Disease Resistance Potential of Diorganotin Complexes in Some Bacteria and Fungi
AU - Savita Belwal
AU - R. V. Singh
Y1 - 2014/01/10
PY - 2014
N1 - https://doi.org/10.11648/j.sjc.20130105.13
DO - 10.11648/j.sjc.20130105.13
T2 - Science Journal of Chemistry
JF - Science Journal of Chemistry
JO - Science Journal of Chemistry
SP - 67
EP - 73
PB - Science Publishing Group
SN - 2330-099X
UR - https://doi.org/10.11648/j.sjc.20130105.13
AB - The reaction of diphenyltin dichloride and dimethyltin dichloride with the ligands of Schiff base lead to the formation of a new series of bioactive organotin (IV) complexes. The isolated products are coloured solids soluble in most of the organic solvents. The bonding and coordination behaviour of these compounds are discussed by the support of electronic, infrared and multinuclear magnetic resonance (1H, 13C and 119Sn NMR) spectral studies. These investigations suggest that the ligands act in a bidentate manner, coordination through the sulphur and nitrogen atoms. Trigonal bipyramidal geometry is proved for 1:1 metal complexes and hexacoordinated geometry is assigned for 1:2 metal complexes. All the complexes are monomeric in nature as indicated by their molecular weight determinations. Conductivity measurements show them to be non-electrolyte as the conductance values in DMF lie in the range of 10-12 ohm-1 cm2 mol-1. Schiff bases and their corresponding organotin complexes have also been screened for their antifungal and antibacterial activities and found to be quite active in this respect. Testing of ligands and their organotin complexes for disease resistance have been successfully studied in vitro and in vivo experiments. Results were quite encouraging and these were compared with the standard pesticides Bavistin and Streptomycin.
VL - 1
IS - 5
ER -

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Author Information

Savita Belwal

Department of Chemical Engineering, CVSR College of Engineering, Hyderabad, India
R. V. Singh

Department of Chemistry, University of Rajasthan, Jaipur 302004, India

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APA Style

Savita Belwal, R. V. Singh. (2014). Evaluation of Disease Resistance Potential of Diorganotin Complexes in Some Bacteria and Fungi. Science Journal of Chemistry, 1(5), 67-73. https://doi.org/10.11648/j.sjc.20130105.13

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ACS Style

Savita Belwal; R. V. Singh. Evaluation of Disease Resistance Potential of Diorganotin Complexes in Some Bacteria and Fungi. Sci. J. Chem. 2014, 1(5), 67-73. doi: 10.11648/j.sjc.20130105.13

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AMA Style

Savita Belwal, R. V. Singh. Evaluation of Disease Resistance Potential of Diorganotin Complexes in Some Bacteria and Fungi. Sci J Chem. 2014;1(5):67-73. doi: 10.11648/j.sjc.20130105.13

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@article{10.11648/j.sjc.20130105.13,
  author = {Savita Belwal and R. V. Singh},
  title = {Evaluation of Disease Resistance Potential of Diorganotin Complexes in Some Bacteria and Fungi},
  journal = {Science Journal of Chemistry},
  volume = {1},
  number = {5},
  pages = {67-73},
  doi = {10.11648/j.sjc.20130105.13},
  url = {https://doi.org/10.11648/j.sjc.20130105.13},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.sjc.20130105.13},
  abstract = {The reaction of diphenyltin dichloride and dimethyltin dichloride with the ligands of Schiff base lead to the formation of a new series of bioactive organotin (IV) complexes. The isolated products are coloured solids soluble in most of the organic solvents. The bonding and coordination behaviour of these compounds are discussed by the support of electronic, infrared and multinuclear magnetic resonance (1H, 13C and 119Sn NMR) spectral studies. These investigations suggest that the ligands act in a bidentate manner, coordination through the sulphur and nitrogen atoms. Trigonal bipyramidal geometry is proved for 1:1 metal complexes and hexacoordinated geometry is assigned for 1:2 metal complexes. All the complexes are monomeric in nature as indicated by their molecular weight determinations. Conductivity measurements show them to be non-electrolyte as the conductance values in DMF lie in the range of 10-12 ohm-1 cm2 mol-1. Schiff bases and their corresponding organotin complexes have also been screened for their antifungal and antibacterial activities and found to be quite active in this respect. Testing of ligands and their organotin complexes for disease resistance have been successfully studied in vitro and in vivo experiments. Results were quite encouraging and these were compared with the standard pesticides Bavistin and Streptomycin.},
 year = {2014}
}

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