Mitochondria: A Key Player in Stem Cell Fate

Nadra Sadaf; Jawaid Ahsan; Saif Ahmad; Rizwanul Haque

doi:doi:10.11648/j.cb.s.2015030201.15

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Mitochondria: A Key Player in Stem Cell Fate

Nadra Sadaf, Jawaid Ahsan, Saif Ahmad, Rizwanul Haque

Published in Cell Biology (Volume 3, Issue 2-1)

Received: 28 February 2015 Accepted: 1 May 2015 Published: 9 June 2015

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Abstract

Mitochondria are highly dynamic organelles that undergo cycles of fusion and fission important for their function, maintenance, and quality control as well as direct or indirect role in different types of stem cells fate decisions. Stem cells have potential for numerous biomedical applications; however the major bottle neck in stem cell field is the stem cell differentiation and maintenance of stemness of stem cells. The regulatory factor involved in stem cell fate decision and stem cell development is not clear. Recent report suggests that mitochondria also play a role in maintenance of pluripotency and cell fate decision. This review mainly cover the role of mitochondria, reactive oxygen species and change in mitochondria structure and functions during cell fate decision in different types of major group of stem cells. This article is a part of special issue on Mitochondria.

Published in	Cell Biology (Volume 3, Issue 2-1) This article belongs to the Special Issue Mitochondria: Implications in Human Health and Diseases
DOI	10.11648/j.cb.s.2015030201.15
Page(s)	31-37
Creative Commons	This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.
Copyright	Copyright © The Author(s), 2015. Published by Science Publishing Group

Keywords

Pluripotent Stem Cells (PSCs), Embryonic Stem Cells (ESCs), Induced Pluripotent Stem Cells (iPSCs), Adult Stem Cell (ASCs), Cancer Stem Cells (CSCs), Mitochondria, Reactive Oxygen Species (ROS)

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Nadra Sadaf, Jawaid Ahsan, Saif Ahmad, Rizwanul Haque. (2015). Mitochondria: A Key Player in Stem Cell Fate. Cell Biology, 3(2-1), 31-37. https://doi.org/10.11648/j.cb.s.2015030201.15

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ACS Style

Nadra Sadaf; Jawaid Ahsan; Saif Ahmad; Rizwanul Haque. Mitochondria: A Key Player in Stem Cell Fate. Cell Biol. 2015, 3(2-1), 31-37. doi: 10.11648/j.cb.s.2015030201.15

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AMA Style

Nadra Sadaf, Jawaid Ahsan, Saif Ahmad, Rizwanul Haque. Mitochondria: A Key Player in Stem Cell Fate. Cell Biol. 2015;3(2-1):31-37. doi: 10.11648/j.cb.s.2015030201.15

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@article{10.11648/j.cb.s.2015030201.15,
  author = {Nadra Sadaf and Jawaid Ahsan and Saif Ahmad and Rizwanul Haque},
  title = {Mitochondria: A Key Player in Stem Cell Fate},
  journal = {Cell Biology},
  volume = {3},
  number = {2-1},
  pages = {31-37},
  doi = {10.11648/j.cb.s.2015030201.15},
  url = {https://doi.org/10.11648/j.cb.s.2015030201.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cb.s.2015030201.15},
  abstract = {Mitochondria are highly dynamic organelles that undergo cycles of fusion and fission important for their function, maintenance, and quality control as well as direct or indirect role in different types of stem cells fate decisions. Stem cells have potential for numerous biomedical applications; however the major bottle neck in stem cell field is the stem cell differentiation and maintenance of stemness of stem cells. The regulatory factor involved in stem cell fate decision and stem cell development is not clear. Recent report suggests that mitochondria also play a role in maintenance of pluripotency and cell fate decision. This review mainly cover the role of mitochondria, reactive oxygen species and change in mitochondria structure and functions during cell fate decision in different types of major group of stem cells. This article is a part of special issue on Mitochondria.},
 year = {2015}
}

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TY  - JOUR
T1  - Mitochondria: A Key Player in Stem Cell Fate
AU  - Nadra Sadaf
AU  - Jawaid Ahsan
AU  - Saif Ahmad
AU  - Rizwanul Haque
Y1  - 2015/06/09
PY  - 2015
N1  - https://doi.org/10.11648/j.cb.s.2015030201.15
DO  - 10.11648/j.cb.s.2015030201.15
T2  - Cell Biology
JF  - Cell Biology
JO  - Cell Biology
SP  - 31
EP  - 37
PB  - Science Publishing Group
SN  - 2330-0183
UR  - https://doi.org/10.11648/j.cb.s.2015030201.15
AB  - Mitochondria are highly dynamic organelles that undergo cycles of fusion and fission important for their function, maintenance, and quality control as well as direct or indirect role in different types of stem cells fate decisions. Stem cells have potential for numerous biomedical applications; however the major bottle neck in stem cell field is the stem cell differentiation and maintenance of stemness of stem cells. The regulatory factor involved in stem cell fate decision and stem cell development is not clear. Recent report suggests that mitochondria also play a role in maintenance of pluripotency and cell fate decision. This review mainly cover the role of mitochondria, reactive oxygen species and change in mitochondria structure and functions during cell fate decision in different types of major group of stem cells. This article is a part of special issue on Mitochondria.
VL  - 3
IS  - 2-1
ER  -

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Author Information

Nadra Sadaf

Centre for Biological Sciences (Biotechnology), Central University of South Bihar, Patna, India
Jawaid Ahsan

Centre for Biological Sciences (Biotechnology), Central University of South Bihar, Patna, India
Saif Ahmad

Dept of Biological Sciences, College of Science and Arts, King Abdulaziz University, Rabegh, Kingdom of Saudi Arabia
Rizwanul Haque

Centre for Biological Sciences (Biotechnology), Central University of South Bihar, Patna, India

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Plain Text BibTeX RIS

APA Style

Nadra Sadaf, Jawaid Ahsan, Saif Ahmad, Rizwanul Haque. (2015). Mitochondria: A Key Player in Stem Cell Fate. Cell Biology, 3(2-1), 31-37. https://doi.org/10.11648/j.cb.s.2015030201.15

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ACS Style

Nadra Sadaf; Jawaid Ahsan; Saif Ahmad; Rizwanul Haque. Mitochondria: A Key Player in Stem Cell Fate. Cell Biol. 2015, 3(2-1), 31-37. doi: 10.11648/j.cb.s.2015030201.15

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AMA Style

Nadra Sadaf, Jawaid Ahsan, Saif Ahmad, Rizwanul Haque. Mitochondria: A Key Player in Stem Cell Fate. Cell Biol. 2015;3(2-1):31-37. doi: 10.11648/j.cb.s.2015030201.15

Copy | Download

@article{10.11648/j.cb.s.2015030201.15,
  author = {Nadra Sadaf and Jawaid Ahsan and Saif Ahmad and Rizwanul Haque},
  title = {Mitochondria: A Key Player in Stem Cell Fate},
  journal = {Cell Biology},
  volume = {3},
  number = {2-1},
  pages = {31-37},
  doi = {10.11648/j.cb.s.2015030201.15},
  url = {https://doi.org/10.11648/j.cb.s.2015030201.15},
  eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.cb.s.2015030201.15},
  abstract = {Mitochondria are highly dynamic organelles that undergo cycles of fusion and fission important for their function, maintenance, and quality control as well as direct or indirect role in different types of stem cells fate decisions. Stem cells have potential for numerous biomedical applications; however the major bottle neck in stem cell field is the stem cell differentiation and maintenance of stemness of stem cells. The regulatory factor involved in stem cell fate decision and stem cell development is not clear. Recent report suggests that mitochondria also play a role in maintenance of pluripotency and cell fate decision. This review mainly cover the role of mitochondria, reactive oxygen species and change in mitochondria structure and functions during cell fate decision in different types of major group of stem cells. This article is a part of special issue on Mitochondria.},
 year = {2015}
}

Copy | Download

TY  - JOUR
T1  - Mitochondria: A Key Player in Stem Cell Fate
AU  - Nadra Sadaf
AU  - Jawaid Ahsan
AU  - Saif Ahmad
AU  - Rizwanul Haque
Y1  - 2015/06/09
PY  - 2015
N1  - https://doi.org/10.11648/j.cb.s.2015030201.15
DO  - 10.11648/j.cb.s.2015030201.15
T2  - Cell Biology
JF  - Cell Biology
JO  - Cell Biology
SP  - 31
EP  - 37
PB  - Science Publishing Group
SN  - 2330-0183
UR  - https://doi.org/10.11648/j.cb.s.2015030201.15
AB  - Mitochondria are highly dynamic organelles that undergo cycles of fusion and fission important for their function, maintenance, and quality control as well as direct or indirect role in different types of stem cells fate decisions. Stem cells have potential for numerous biomedical applications; however the major bottle neck in stem cell field is the stem cell differentiation and maintenance of stemness of stem cells. The regulatory factor involved in stem cell fate decision and stem cell development is not clear. Recent report suggests that mitochondria also play a role in maintenance of pluripotency and cell fate decision. This review mainly cover the role of mitochondria, reactive oxygen species and change in mitochondria structure and functions during cell fate decision in different types of major group of stem cells. This article is a part of special issue on Mitochondria.
VL  - 3
IS  - 2-1
ER  -

Copy | Download